Cardiopreliminary · human dataDiscovery of the day
A network meta-analysis of 15 randomised trials in peripheral artery disease ranked supervised exercise therapy plus medication highest for avoiding amputation, and exercise combined with revascularisation and medication highest for all-cause mortality and blood flow to the limb. The rankings are probabilities, not proof of superiority.
What it shows: Systematic review and network meta-analysis of only 15 RCTs totalling 1,461 participants, with sparse direct comparisons, heterogeneous populations and possible publication bias; overall certainty was mainly moderate to low, and SUCRA values indicate relative ranking probability rather than definitive clinical superiority.Study · Front Med (Lausanne)
Full breakdown →Learn more →Try the calculator →Impact of endovascular revascularization, pharmacotherapy, and supervised exercise therapy on long-term cardiovascular, cerebrovascular, mortality, and limb outcomes in patients with peripheral artery disease: a systematic review and network meta-analysis. Front Med (Lausanne) 2026