Fact of the day

Friday, 18 September 2026

Gut & Microbiomewell supported · human dataDiscovery of the day

A systematic review of 87 randomised trials in 6086 adults with overweight or obesity found most diet, exercise and supplement interventions did not significantly shift overall gut microbiome diversity, though probiotic intake was linked to more Lactobacillus alongside reduced body weight and body fat.

Study design
Systematic review
Journal
Obes Rev
Evidence
well supported

What it shows: Take this as a map rather than a verdict: a sweep of 87 trials in 6086 adults found methods and results varied so much that findings could not be properly pooled. Trial quality ranged from very low to moderate, so the probiotic and weight link is a promising association, not proof.Systematic review · Obes Rev

Impacts of Lifestyle and Microbiota-Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review. Obes Rev 2026Read the study →

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