Cardiowell supported · human data

Energy drinks push blood pressure up mid-workout

A meta-analysis of 21 randomised trials found that caffeinated energy drinks raised systolic blood pressure by 9.02 mmHg and heart rate by 2.86 bpm during exercise in healthy adults, while diastolic blood pressure was unchanged.

Compiled by FitTools from the study cited below

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Added to Pulse 9 August 2026

Study design
Meta-analysis
Evidence
well supported
Published
9 August 2026

Key takeaway

What it shows: Solid pooled evidence, but a narrow window on it: 21 randomised trials covering just 296 healthy adults, mostly men, during aerobic exercise only. The data were too thin to say anything about heart rhythm effects, which is the question many readers will actually have.

Study details

Design
Meta-analysis
Authors
Grinberg N, Benkhedda K, Barber J, Krahn AD, La Vieille S
Journal
Appl Physiol Nutr Metab
Published
2022
Added to Pulse
9 August 2026

Why it matters

Caffeinated energy drinks are routinely consumed shortly before training, yet most of what we know about their cardiovascular effects comes from measurements taken at rest. Exercise already raises heart rate and blood pressure, so any extra strain from a stimulant drink lands precisely when the cardiovascular system is working hardest. The review's authors note that the impact of these drinks on the cardiovascular response to exercise has not been well described. This meta-analysis set out to quantify that response using only randomised controlled trials.

What they did

The researchers systematically reviewed and meta-analysed randomised controlled trials that tested the acute effects of caffeinated energy drinks on cardiovascular responses during dynamic, aerobic exercise. Twenty-one trials met the inclusion criteria, covering 296 healthy adults, of whom 224 were male and 72 were female. The pooled outcomes were heart rate, systolic blood pressure and diastolic blood pressure during exercise, each compared against control conditions. The team also attempted to assess rate pressure product and exercise-induced arrhythmia.

What they found

During exercise, heart rate was 2.86 bpm higher with energy drinks than with controls, a modest difference that was remarkably consistent across trials. Systolic blood pressure rose by a larger 9.02 mmHg on average, with a confidence interval spanning 4.25 to 13.79 mmHg. Diastolic blood pressure, by contrast, was similar with and without the drinks. There were insufficient data to draw any conclusion about rate pressure product or about heart rhythm disturbances during exercise.

Where it fits

The novelty here is the setting: rather than testing cardiovascular effects at rest, this review directly assessed what happens while people are actually exercising, which is when many energy drinks are consumed. The heart rate change is small, but the systolic blood pressure rise is more substantial, and the authors single out its relevance to people prone to hypertension. Important gaps remain, particularly around arrhythmia, where the trial evidence was too thin to analyse. The evidence also skews heavily male, with only 72 of the 296 participants being women.

What it means for you

If you drink an energy drink before training, this review is a reason to think it does more than sharpen your focus: it appears to add measurably to the blood pressure load your heart carries during the session. The participants were healthy adults and the heart rate change was modest, so this is not evidence of harm in that group. It is, however, a reason for anyone with high blood pressure, or a tendency towards it, to know that these drinks' cardiovascular effects show up during exercise itself, not just at rest.

The source

Effects of caffeinated energy drinks on cardiovascular responses during exercise in healthy adults: a systematic review and meta-analysis of randomized controlled trials. Appl Physiol Nutr Metab 2022

DOI: 10.1139/apnm-2021-0807

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