Cardiowell supported · human data

Squeezing a handgrip lowers blood pressure more than cardio in older adults

Pooled results from 92 randomised trials found that aerobic, resistance, combined and isometric handgrip training all significantly lowered blood pressure in older adults with hypertension, with isometric handgrip training producing the greatest reductions. Combined training also lowered LDL and raised HDL.

Compiled by FitTools from the study cited below

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Added to Pulse 29 October 2026

Study design
Meta-analysis
Evidence
well supported
Published
29 October 2026

Key takeaway

What it shows: Convincing on direction, less settled on detail: results pooled from 92 trials in older adults with high blood pressure, where people were assigned at random. The trials varied in how training was delivered, so the ideal dose, intensity and length remain unsettled.

Study details

Design
Meta-analysis
Authors
Hejazi K, Iraj ZA, Saeidi A, Hackney AC, Laziri F, Suzuki K, et al.
Journal
Arch Gerontol Geriatr
Published
2025
Added to Pulse
29 October 2026

Why it matters

High blood pressure is one of the biggest risk factors for cardiovascular disease, and it becomes more common and harder to manage with age. Keeping blood pressure within the normal range can prevent or delay complications, and exercise is one of the few tools that costs little and carries broad benefits. But exercise comes in many forms: aerobic work, resistance training, combinations of the two, tai chi and isometric holds. For older adults with hypertension, it has never been clear which style delivers the biggest blood pressure payoff, or how the styles compare on cholesterol and triglycerides.

What they did

The researchers searched five databases from inception to March 2024 and identified 1998 articles, of which 92 randomised controlled trials in older adults with hypertension met their inclusion criteria. They pooled the results using a random-effects model, estimating how much each style of training shifted systolic and diastolic blood pressure. They also examined blood lipids, including LDL, HDL and triglycerides, across the different training types. The styles compared included aerobic training, resistance training, combined aerobic and resistance training, isometric handgrip training and tai chi.

What they found

Aerobic, resistance, combined and isometric handgrip training all produced significant reductions in both systolic and diastolic blood pressure. Isometric handgrip training led to greater blood pressure reductions than aerobic, resistance, combined or tai chi training. On blood fats, combined training lowered LDL and raised HDL, resistance training lowered triglycerides, and aerobic training also raised HDL. Resistance training and tai chi did not significantly raise HDL, a reminder that the lipid benefits depend on the type of exercise performed.

Where it fits

The result extends a growing body of work suggesting isometric exercise punches above its weight for blood pressure, and it does so specifically in older adults, a group often steered toward gentle aerobic activity alone. It also confirms that cholesterol and triglyceride benefits are not interchangeable across training styles, with combined training moving the most markers. The authors note that further studies are needed to pin down the prescriptions, including intensity, frequency and duration, that maximise these gains. How handgrip training performs over years rather than weeks also remains open.

What it means for you

For anyone watching their blood pressure climb, or supporting parents who manage hypertension, the message is that essentially every form of structured exercise helps. The surprise is that simple isometric handgrip work, squeezing against resistance and holding, outperformed sweatier options on blood pressure specifically. That does not make it a replacement for aerobic or resistance training, which carried their own benefits for cholesterol and triglycerides. It is a reason to see blood pressure control as trainable through more than one door, including a very undemanding one.

The source

Differential effects of exercise training protocols on blood pressures and lipid profiles in older adults patients with hypertension: A systematic review and meta-analysis. Arch Gerontol Geriatr 2025

DOI: 10.1016/j.archger.2024.105737

Read the study →

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