Mindwell supported · human data

Lifting weights eased depression in under-26s

In a meta-analysis of 10 randomised trials with 376 people aged 26 or under with clinically elevated symptoms, resistance training produced large reductions in both depression and anxiety symptoms, with high-certainty evidence for depression.

Compiled by FitTools from the study cited below

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Added to Pulse 18 August 2026

Study design
Meta-analysis
Evidence
well supported
Published
18 August 2026

Key takeaway

What it shows: One of the stronger exercise and mood findings: results pooled from 10 trials where 376 young people were assigned at random, rated high certainty for depression, though the size of the benefit varied a lot between trials and none tracked whether it lasted after the programme ended.

Study details

Design
Meta-analysis
Authors
Marinelli R, Parker AG, Levinger I, Bourke M, Patten R, Woessner MN, et al.
Journal
Early Interv Psychiatry
Published
2024
Added to Pulse
18 August 2026

Why it matters

Most of the evidence for exercise as a mental health treatment centres on aerobic activity, and much of it comes from adults. Whether resistance training on its own can reduce depression and anxiety symptoms in young people is a distinct and practical question, because lifting is accessible, scalable and deliverable in schools, clinics and community settings. This review set out to determine the treatment effect of resistance training specifically, in people aged 26 or younger whose symptoms were already clinically elevated rather than in the general population. That focus on symptomatic young people makes it a genuine treatment question, not a wellness one.

What they did

The researchers searched MEDLINE, PsychINFO and PubMed for randomised controlled trials published in English between January 1980 and September 2023. Eligible trials had to include at least 4 weeks of resistance training and participants aged 26 years or younger with clinically elevated anxiety and depression symptoms. A random-effects meta-analysis compared symptom change in the training groups against control groups. Ten trials qualified, covering 376 participants, 209 of them female and 127 male, across educational, clinical and community settings, and study quality and certainty of evidence were formally assessed.

What they found

Resistance training was associated with a large and statistically significant reduction in depressive symptoms, with a pooled effect of -1.06, and a similarly large reduction in anxiety symptoms at -1.02. The benefit was not uniform: the trials varied substantially in how big the effect was for both outcomes. On quality, six trials had a low risk of bias and four raised some concerns. The certainty of the evidence was rated high for depressive symptoms and moderate for anxiety symptoms.

Where it fits

This puts resistance training alongside better-studied aerobic exercise as a credible non-drug option for youth mental health, and the high certainty rating for depression is notable for a field where evidence is often graded down. The pooled effects here are large by the standards of exercise and mood research. The gaps are equally clear: none of the trials followed participants long term, so nobody knows whether improvements persist after a programme ends, and the variation between trials leaves open which formats work best.

What it means for you

For a young person, or anyone who cares for one, this is a reason to see strength training as more than a physique pursuit: the pooled trial evidence suggests it can meaningfully reduce symptoms of depression and anxiety when symptoms are elevated. It also matters that the trials worked across schools, clinics and community settings, suggesting the effect is not confined to one environment. This is evidence about an option, not a substitute for professional care.

The source

Resistance training and combined resistance and aerobic training as a treatment of depression and anxiety symptoms in young people: A systematic review and meta-analysis. Early Interv Psychiatry 2024

DOI: 10.1111/eip.13528

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