Fact of the day

Monday, 5 October 2026

Metabolic & GLP-1well supported · human dataDiscovery of the day

In pooled trial data from people with type 2 diabetes, intermittent fasting lowered HbA1c, fasting glucose and body weight over the short term (under 3 months) compared with other diets, but performed no better in the long term and the metabolic benefits disappeared once the fasting stopped.

Study design
Meta-analysis
Journal
Nutr Res
Evidence
well supported

What it shows: A fair verdict on durability: results pooled from 12 trials with 966 people with type 2 diabetes, though the studies disagreed with each other a fair amount, so treat the exact effect sizes loosely. The long-term data showed no advantage over other diets, and the gains vanished after people stopped fasting.Meta-analysis · Nutr Res

The metabolic effects of intermittent fasting in patients with type 2 diabetes exist in the short term but disappear after its discontinuation: A systematic review and meta-analysis of randomized controlled trials. Nutr Res 2025Read the study →

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