well supported · human dataDiscovery of the day
In adults with early-stage cardio-kidney-metabolic syndrome, those with the highest triglyceride-glucose index scores had up to 45% higher risk of developing cardiovascular disease than those with the lowest, in pooled data from nine studies that followed people over time.
- Study design
- Meta-analysis
- Journal
- BMC Cardiovasc Disord
- Evidence
- well supported
What it shows: A consistent link, not proof of cause: it pools nine studies that followed people rather than testing anything on them, and the studies disagreed with each other quite a bit. The populations studied were not very diverse, so the picture may differ elsewhere.Meta-analysis · BMC Cardiovasc Disord
Association between triglyceride-glucose-related indices and cardiovascular disease risk in population with cardio-kidney-metabolic syndrome stages 0-3: a systematic review and meta-analysis. BMC Cardiovasc Disord 2026Read the study →