Supplementspreliminary · human data

Peppermint oil lowered blood pressure within 20 days

Twice-daily peppermint oil supplementation, 100 μL per day, lowered systolic blood pressure by 8.48 mmHg relative to placebo after 20 days in a randomised trial of 40 adults with pre-hypertension and stage 1 hypertension. Readings fell from 130.05 to 121.97 mmHg in the peppermint group while the placebo group stayed flat.

Compiled by FitTools from the study cited below

The citation, figures and study details on this page are taken mechanically from the source record. No human editor has reviewed it.

Added to Pulse 23 August 2026

Study design
RCT
Evidence
preliminary
Published
23 August 2026

Key takeaway

What it shows: Encouraging but far from settled: one 20-day trial in just 40 people with mildly raised blood pressure, run by a single research group. It needs repeating in bigger groups, and for longer, before peppermint earns a place alongside proven blood pressure care.

Study details

Design
RCT
Authors
Sinclair J, Sant B, Du X, Shadwell G, Dillon S, Butters B, et al.
Journal
PLoS One
Published
2026
Added to Pulse
23 August 2026

Why it matters

High blood pressure is the single biggest risk factor for cardiovascular disease and death, and it carries an enormous cost for health systems worldwide. Medication is the standard response, yet the trial's authors note that its long-term effectiveness remains ambiguous and that side effects put many people off. That creates a genuine appetite for simple, low-cost options that people will actually stick with. Peppermint is rich in menthol and flavonoids, compounds the researchers suggest may be relevant to blood pressure, so this trial set out to test whether a daily peppermint oil supplement could shift readings in people whose blood pressure is raised but not yet severe.

What they did

The team ran a 20-day trial in which participants were assigned at random to one of two arms. Forty adults with pre-hypertension or stage 1 hypertension received either 100 μL per day of peppermint oil, taken as a twice-daily supplement, or a peppermint-flavoured placebo designed to be indistinguishable. The primary outcome was the between-group difference in systolic blood pressure from baseline to 20 days. The researchers also tracked body measurements, blood markers, diastolic pressure, resting heart rate, psychological wellbeing and sleep. Everyone randomised was included in the analysis, with results adjusted for each person's starting values.

What they found

After 20 days, systolic blood pressure in the peppermint group was 8.48 mmHg lower than in the placebo group once baseline readings were accounted for, a difference the authors report as statistically significant and sizeable. The peppermint arm fell from an average of 130.05 mmHg to 121.97 mmHg, while the placebo arm essentially stood still, moving from 130.93 to 131.05 mmHg. The supplement was well tolerated: only one person dropped out and only one adverse event was recorded, both in the peppermint arm, and compliance in that group reached 93.3%. The abstract does not report how the secondary outcomes changed.

Where it fits

Plenty of plant compounds have been floated as blood pressure aids, and most fade when tested against placebo, so a controlled result of this size is notable. Still, this is a single short trial in 40 people from one research group, and 20 days says nothing about whether the effect lasts for months or translates into fewer heart attacks or strokes. The finding needs replication in larger and more diverse groups before peppermint could be considered more than a promising lead. It also remains unclear which component, whether menthol, flavonoids or something else, might account for the effect.

What it means for you

If your blood pressure sits in the raised-but-not-severe range, this is a reason to keep an eye on peppermint research rather than a green light to self-treat. The trial suggests a cheap, well-tolerated supplement moved readings meaningfully over 20 days, which is genuinely interesting for anyone thinking about heart health. But one small trial cannot tell you whether the effect holds up over time or applies to you, and raised blood pressure remains something most people monitor with a clinician rather than the supplement aisle. The honest position for now is watchful curiosity.

The source

Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial. PLoS One 2026

DOI: 10.1371/journal.pone.0344538

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