Supplement · Minerals

Lithium orotate

Also known as: Low-dose lithium

Low-dose lithium sold for mood, without the trial evidence of prescription lithium.

Evidence
Unproven· human data
Sources cited
1
Last reviewed
22 July 2026

Lithium orotate is a low-dose lithium salt sold over the counter for mood and 'brain health', trading on the fact that prescription lithium is an effective mood stabiliser.

But that prescription evidence is at much higher, carefully monitored doses; the low over-the-counter doses have essentially no controlled outcome evidence, and lithium's narrow safety margin normally warrants blood monitoring. Genuine mood disorders are a medical matter, not a case for self-dosing a mineral supplement.

Sources