Supplement

Melatonin

A sleep-timing hormone that's useful for jet lag, less so as a nightly sleeping pill.

Evidence
Silver· human data
Sources cited
1
Last reviewed
22 July 2026

What it is

Melatonin is a hormone that signals "time for sleep" to your body clock. That makes it a body-clock tool more than a sedative, a distinction that explains where it works well and where it disappoints.

What the evidence shows

Jet lag and body-clock timing. Gold· human data Its strongest evidence is for shifting the body clock, jet lag and delayed sleep timing.

As a general sleeping aid. Silver· human data It can modestly help you fall asleep a bit faster, but it is not a powerful sleeping pill, and its long-term nightly use is not well studied.

Who it suits

Travellers crossing time zones and people whose sleep timing has drifted late, more than someone simply after a stronger nightly sedative.

Practical notes

Timing often matters more than amount: because it signals your body clock, when you take it is important, and lower amounts at the right time can work as well as larger ones. It is a hormone, so avoid it in pregnancy and seek medical advice for children or ongoing use, and note it is prescription-only in some countries. Sort your routine first with the sleep calculator.

Sources

Frequently asked questions

Does melatonin help you sleep?
Its strongest evidence is for shifting the body clock in jet lag and delayed sleep timing, rather than as a sedative. It can modestly help you fall asleep a bit faster, but it's not a powerful sleeping pill.
Is timing more important than dose?
Often, yes. Because it signals 'time for sleep' to your body clock, when you take it matters a lot, and lower amounts taken at the right time can work as well as larger ones.
Is it safe to take every night?
It's widely used short-term, but the long-term safety of nightly use isn't well established, and it's a hormone. It's best treated as a targeted tool rather than a default nightcap, with medical advice for ongoing use.
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