Supplement · Nootropics & cognition

Citicoline (CDP-choline)

Also known as: CDP-choline

A brain-targeted choline donor with early evidence for attention and memory.

Evidence
Silver· human data
Sources cited
1
Last reviewed
22 July 2026

Citicoline (CDP-choline) supplies choline and cytidine and supports the brain's phospholipid and acetylcholine systems, making it a popular focus and memory nootropic.

Some human trials, including in healthy adults and in age-related memory complaints, report modest improvements in attention and memory, and it is used clinically for cognition in some countries. The evidence is promising but early; it is one of the better-tolerated choline sources.

Sources