Saffron extract

Silver· human data

Also known as: Crocus sativus

A spice extract with reasonably encouraging trials for low mood.

Saffron is a culinary spice whose standardised extract has been studied for mood, with a more encouraging evidence base than many mood supplements.

Several trials suggest saffron can improve symptoms of mild-to-moderate depression, in some cases comparably to low-dose antidepressants, and it appears in mood and PMS formulas. Studies are still relatively small; it should not replace treatment for significant depression, which is a medical matter.

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Written and reviewed by Mathew Beale, MSc Biotechnology, University of Reading.

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