9 studies

Environment

  1. Environmentwell supported · human dataAdded 8 August 2026
    Cold waves carry a 40% higher death risk for people with diabetes

    Pooled data from eight studies link cold-wave exposure to a 40% increase in diabetes-related mortality risk (relative risk 1.40); the rise in diabetes-related illness was smaller and not statistically significant.

    What it shows: Meta-analysis of eight observational studies; the morbidity estimate was not statistically significant (its confidence interval crossed 1) and risk varied across studies, suggesting environmental and healthcare disparities between settings.Meta-analysis · Front Public Health

  2. Environmentpreliminary · human dataAdded 6 August 2026
    Summer ozone tracks with heart-death risk

    In a meta-analysis of cohort studies, every 10 µg/m3 increase in long-term ozone exposure was associated with modestly higher cardiovascular mortality (RR 1.0105) and cardiovascular morbidity (RR 1.0578). The mortality association was clearer for warm-season ozone (RR 1.0186) than for annual average exposure (RR 0.9971), and estimates were higher in females (RR 1.1135) than males (RR 1.0707).

    What it shows: Meta-analysis of observational cohort studies, so it shows association and not causation; the authors describe the long-term ozone evidence as sparse, the male and Asia-region estimates had confidence intervals crossing no effect, and most data came from Europe and the USA.Review · China CDC Wkly

  3. Environmentpreliminary · human dataAdded 6 August 2026
    Living near lead-releasing sites tied to weaker memory

    Living closer to a lead-releasing facility was associated with poorer episodic memory two years later in two cohorts of older adults (n = 1638 and n = 741): every 5 km closer corresponded to episodic memory scores 0.05 standard deviations lower.

    What it shows: Observational data from two cohorts of older adults; proximity to a facility is a stand-in for actual lead exposure, which was not directly measured. Association, not causation, and residual confounding is possible despite adjustment.Meta-analysis · Alzheimers Dement

  4. Environmentwell supported · human dataAdded 6 August 2026
    Particle pollution and death: likely cause, not chance

    A critical appraisal of 15 published reviews concluded that the short-term association between airborne particles and cardiopulmonary mortality is valid and satisfies most standard criteria for causality, with effects observed even where air quality standards were respected.

    What it shows: A 2001 critical assessment of the arguments in 15 existing reviews of ecological time-series studies, not a pooled analysis of individual data; time-series designs compare days rather than people, and the exposure landscape has changed since publication.Meta-analysis · J Air Waste Manag Assoc

  5. Environmentpreliminary · human dataAdded 6 August 2026
    Beijing's cleaner air came with a smaller daily death toll

    Across five periods in Beijing between 1990 and 2017, concentrations of SO2, NO2, PM10 and PM2.5 fell by up to 42%, 10%, 33% and 15%, and the estimated short-term mortality effect of each pollutant shrank alongside them: PM2.5's effect on cardiovascular and respiratory deaths falling by up to 0.33% and 0.13%.

    What it shows: Longitudinal comparative study in one city: published effect estimates for 1990-2013 pooled by random-effects meta-analysis and combined with newly analysed 2015-2017 daily data. The design is ecological, so parallel changes in healthcare, smoking or population structure cannot be excluded.Meta-analysis · Chemosphere

  6. Environmentwell supported · human dataAdded 6 August 2026
    Long-term PM2.5 linked to worse Covid outcomes

    In a meta-analysis of cohort studies with individual-level data, each 1 µg/m3 increase in long-term PM2.5 exposure was associated with a 4% higher risk of SARS-CoV-2 infection, an 11% higher risk of COVID-19 hospitalisation and a 9% higher risk of COVID-19 death; NO2 was associated with hospitalisation and death, while ozone showed no association with any outcome.

    What it shows: Systematic review and random-effects meta-analysis restricted to cohort studies with individual-level data, pooled only where more than three studies existed per exposure-outcome pair. Observational throughout, so residual confounding remains possible, and country of study explained much of the heterogeneity between results.Meta-analysis · Environ Pollut

  7. Environmentpreliminary · human dataAdded 6 August 2026
    Cold snaps raise stroke deaths days after they hit

    Across 12 counties in Hubei, China, covering 42 739 stroke deaths between 2009 and 2012, cold spells were associated with a pooled stroke mortality risk of 1.180 at lags of 3-14 days, with the effect appearing after a delay of 2-3 days and lasting about 10 days, while heatwaves carried a pooled risk of 1.114 concentrated in the first 0-2 days.

    What it shows: Observational multivariate meta-analysis pooling daily mortality and weather records from 12 counties in one Chinese province over four years; ecological time-series design with no individual data, and county-level estimates varied widely, from 0.968 to 1.523 for cold spells.Meta-analysis · Zhonghua Liu Xing Bing Xue Za Zhi

  8. Environmentwell supported · human dataAdded 6 August 2026
    Extreme cold outranks heat as the deadlier extreme

    Pooling 58 observational studies, extreme cold carried the highest all-cause mortality risk at a relative risk of 1.478, above heatwaves at 1.280 and extreme heat at 1.145; heatwaves were also associated with more hospitalisations (1.060) and emergency department visits (1.047).

    What it shows: Systematic review and meta-analysis of 58 observational studies published between 2000 and 2024, so all estimates are associations from population records rather than controlled comparisons; definitions of extreme cold, extreme heat and heatwave vary between studies, and few studies covered length of stay or costs.Meta-analysis · Int J Hyg Environ Health

  9. Environmentwell supported · human dataAdded 6 August 2026
    Heat plus high ozone: mortality risks stack up

    In a meta-analysis of 28 studies, days combining heat with high ozone were associated with a 17% higher overall mortality risk than days without co-exposure, with elevated cardiovascular and respiratory mortality and increased risks across age and gender groups and in urban areas.

    What it shows: Systematic review of 78 studies with 28 pooled by random-effects meta-analysis; all observational, with the authors flagging risk of bias from inadequate confounder adjustment and unclear handling of missing data, plus inconsistent definitions of what counts as a compound heat-ozone event.Meta-analysis · Environ Pollut

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