Pooling the only three eligible trials, totalling 37 untrained adults, blood flow restriction combined with neuromuscular electrical stimulation produced a medium but statistically non-significant effect on lower-limb muscle growth compared with control (d = 0.64, 95% CI -0.37 to 1.65, p = 0.176).
What it shows: Systematic review and meta-analysis, but the entire evidence base is three studies in 37 untrained healthy adults aged 18-64, lower limb only, interventions of at least 14 days; the pooled effect was not statistically significant and the confidence interval crosses zero.Meta-analysis · Sci Rep