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  1. Women's Healthwell supported · human dataAdded 16 August 2026
    Lifting weights rebuilds strength and stamina after menopause

    Pooled results from 12 randomised trials show resistance training significantly improves maximal oxygen uptake and both upper and lower body strength in healthy postmenopausal women; the authors back a frequency of 3 days per week in 60-min sessions. Effects on bone density and body composition remain debated.

    What it shows: Solid footing: results pooled from 12 trials where healthy postmenopausal women were assigned at random to resistance training or a control group, and the strength gains were large and consistent. Bone density and body composition are still contested, so this is a fitness finding, not a fracture prevention one.Meta-analysis · Climacteric

  2. Bones & Jointswell supported · human dataAdded 16 August 2026
    Kegels ease low back pain, not just bladder trouble

    Across 19 randomised trials (456 people doing the exercises, 470 controls), pelvic floor muscle strengthening reduced low back pain intensity more than control care, with the biggest reductions in postpartum and pregnant women.

    What it shows: Decent evidence with a wobble: results pooled from 19 trials all pointed towards less pain after pelvic floor training, but the trials disagreed with each other a lot, so the true size of the benefit is uncertain. The clearest signal came from women during and after pregnancy, so it may not transfer equally to everyone else.Meta-analysis · Neurol Sci

  3. Supplementspreliminary · human dataAdded 16 August 2026
    Fish oil left blood fats and blood sugar unmoved in diabetes trials

    Pooled results from 11 trials in people with diabetes found omega-3 supplements had no significant effect on triglycerides, cholesterol, HbA1c, fasting glucose or inflammation markers. Fasting insulin, insulin resistance and corneal nerve health did improve, though the authors call these findings hypothesis-generating.

    What it shows: Take this as a signal, not a verdict: results were pooled from 11 small trials and the reviewers rated the certainty of the evidence as very low to low. The nulls on blood fats and blood sugar are as informative as the insulin finding, but bigger, longer trials are needed before either counts as settled.Review · Curr Dev Nutr

  4. Women's Healthpreliminary · human dataAdded 16 August 2026
    Exercise improves insulin and cholesterol in PCOS, on shaky evidence

    In pooled trials, exercise improved fasting insulin, insulin resistance, total and LDL cholesterol, triglycerides, aerobic fitness, waist circumference and body fat in women with PCOS compared with usual care, though the underlying evidence was graded low or very low quality.

    What it shows: Encouraging but fragile: pooled results from 18 trials in women with PCOS, mostly graded low or very low quality, with modest effects and wide margins that shifted when single trials were added or removed.Meta-analysis · Syst Rev

  5. Supplementswell supported · human dataAdded 16 August 2026
    Creatine's body composition effect is real but small

    Across 143 randomised trials, creatine supplementation increased body mass by 0.86 kg and fat-free mass by 0.82 kg while reducing body fat percentage by 0.28 points; effects were larger when a maintenance dose was used or resistance training was performed alongside.

    What it shows: About as strong as supplement evidence gets: results pooled from 143 trials where people were assigned at random, with unusually consistent findings. Even so, the average gain was under a kilogram of lean mass, and one author has ties to a creatine manufacturer.Meta-analysis · J Int Soc Sports Nutr

  6. Women's Healthpreliminary · human dataAdded 16 August 2026
    Diet tweaks may ease menopausal mood dips, but which ones is unclear

    Nutritional interventions modestly reduced depressive and anxiety symptoms in women during and after the menopausal transition across 32 placebo-controlled trials, but the studies varied so much that the true effect of any single approach remains unclear.

    What it shows: Promising but murky: results pooled from 32 placebo-controlled trials, yet the diets, supplements and mood questionnaires varied so much that the studies disagreed with each other, and the authors say the real effect of any one approach is still unclear.Meta-analysis · Menopause

  7. Recoverywell supported · human dataAdded 16 August 2026
    Ice baths restore performance after team sport, but not the soreness

    Cold water immersion aided recovery of jump and sprint performance 24 hours after team sport and reduced perceived fatigue at 72 hours in pooled data from 23 studies; neither cold water immersion nor contrast water therapy improved perceived muscle soreness.

    What it shows: Reasonable evidence for athletes: results pooled from 23 studies with 606 team sport players. The benefits were selective, with some performance and fatigue measures improving while perceived soreness did not, so it is not a blanket recovery fix.Meta-analysis · J Strength Cond Res

  8. Nutritionwell supported · human dataAdded 16 August 2026
    Fasting beats plain calorie cutting by less than a kilogram of fat

    Over six months or longer, intermittent fasting reduced body weight by 2.84 kg, fat mass by 3.06 kg and waist circumference by 3.85 cm versus a control diet in adults with overweight or obesity; against continuous calorie restriction its edge shrank to 0.70 kg more fat lost.

    What it shows: Strong for a diet question: results pooled from 24 trials of 2032 adults with overweight or obesity, all lasting six months or more. The edge over ordinary calorie cutting was real but small, so neither approach clearly wins.Meta-analysis · Obes Rev

  9. Environmentwell supported · human dataAdded 16 August 2026
    Living near traffic is linked to earlier death and adult-onset asthma

    Long-term exposure to traffic-related air pollution is associated with higher all-cause, circulatory, ischaemic heart disease and lung cancer mortality, as well as asthma onset in children and adults, with high or moderate-to-high confidence across 353 studies.

    What it shows: A strong and carefully vetted signal: an independent expert panel reviewed 353 studies and rated confidence high or moderate-to-high for these links. Almost all the research followed people rather than testing anything, so it shows association, not proof of cause.Meta-analysis · Environ Int

  10. Women's Healthwell supported · human dataAdded 16 August 2026
    Any exercise builds bone after menopause, lifting or not

    In postmenopausal women, exercise significantly improved bone mineral density at the lumbar spine, femoral neck and total hip across 84 exercise groups, and the benefit held largely regardless of whether the training was resistance work, weight-bearing exercise or a mix.

    What it shows: Strong evidence for the headline effect: results pooled from controlled trials covering 84 exercise groups of postmenopausal women, each lasting at least six months. The pooled data are too coarse to say which precise routine builds the most bone, a limit the authors themselves flag.Meta-analysis · Calcif Tissue Int

  11. Sleeppreliminary · human dataAdded 16 August 2026
    Cannabis barely changes sleep; quitting it is what wrecks it

    Sleep-lab recordings show cannabis does not consistently alter sleep duration, latency, wake time, efficiency or sleep staging. Withdrawal from regular use, by contrast, was consistently linked to disturbed sleep: shorter total sleep, slower sleep onset and REM rebound.

    What it shows: Treat this as an early correction rather than a final verdict: 18 sleep-lab studies were reviewed and nine pooled, but many were small, doses and products varied widely, and the authors call the evidence base very limited. The withdrawal effects were the most consistent finding across studies.Meta-analysis · Sleep Med Rev

  12. Nutritionpreliminary · human dataAdded 16 August 2026
    A daily juice did not crowd out whole fruit and veg

    In a four-week trial of 42 adults who ate little fruit and veg, allowing one daily portion of juice or smoothie within UK 5-a-day advice did not significantly reduce whole fruit and vegetable intake: 6.6 portions a day versus 8.9 for whole produce alone, against 2.45 in the control group. The group including juice also reported lower depression symptoms than control, with no differences in anxiety, gut symptoms or metabolic markers.

    What it shows: Suggestive but thin: one four-week trial in 42 healthy adults who were eating two servings a day or fewer, and every group was handed weekly cash for produce, so it tells you little about ordinary shopping. The mood result was a secondary outcome and the work was paid for by a fruit juice industry body, which is worth holding in mind.Study · Br J Nutr

  13. Bones & Jointspreliminary · human dataAdded 15 August 2026
    Rest was the old prescription for chronic pain; the evidence backs movement

    An overview of 21 Cochrane reviews covering 381 studies and 37,143 adults with chronic pain found exercise caused few adverse events and tended to improve pain severity and physical function, though most effects were small to moderate and the underlying evidence quality was low.

    What it shows: Reassuring on safety, less certain on how much relief to expect: this sweep of all the studies covered 381 trials with 37,143 adults, but most individual trials had fewer than 50 people and rarely followed anyone beyond three to six months. The clearest signal is that exercise did little harm.Meta-analysis · Cochrane Database Syst Rev

  14. Gut & Microbiomepreliminary · human dataAdded 15 August 2026
    Probiotics tighten the gut barrier, at least on lab markers

    Pooled data from 26 randomised trials in 1,891 people found probiotics improved laboratory markers of gut barrier function, including lower serum zonulin, endotoxin and LPS, and also reduced inflammatory markers such as CRP, TNF-α and IL-6 compared with control groups.

    What it shows: Encouraging but marker-deep: results pooled from 26 trials with 1,891 people showed changes in blood and laboratory measures of gut leakiness, not in symptoms people actually notice. The authors themselves say higher-quality trials are needed before drawing a definitive conclusion.Meta-analysis · Front Immunol

  15. Trainingwell supported · human dataAdded 15 August 2026
    Heavy weights win for strength, but any load builds muscle

    Pooled evidence from 178 randomised trials shows any resistance training routine builds strength and muscle in healthy adults compared with no exercise. Loads above 80% of one repetition maximum ranked best for strength, while all loads grew muscle comparably.

    What it shows: About as trustworthy as training evidence gets: results pooled from 178 trials with 5097 people for strength and 119 trials with 3364 people for muscle size, and the rankings survived deliberate stress testing. Most sensible routines performed similarly, so the top-ranked recipes beat the rest by small margins.Meta-analysis · Br J Sports Med

  16. Mindwell supported · human dataAdded 15 August 2026
    Cannabis eases chronic pain in trials, but is tied to psychosis and car crashes

    An umbrella review of 101 meta-analyses found high-certainty evidence that cannabis based medicines reduce chronic pain and that cannabidiol reduces seizures in epilepsy, but convincing evidence linking cannabis to psychosis in the general population, car crashes in drivers, and low birth weight in pregnancy. The authors conclude cannabis should be avoided in adolescence, in pregnancy, before driving and by anyone prone to mental health problems.

    What it shows: Strong for the headline harms: this graded 101 separate pooled analyses of the evidence, and the psychosis, driving and pregnancy links reached the top credibility tier. Much of the harm evidence still comes from following users rather than experiments, so cause cannot be fully pinned down.Systematic review · BMJ

  17. Cardiowell supported · human dataAdded 15 August 2026
    Cardio for the engine, weights for the muscle: older adults may need both

    A meta-analysis of 38 randomised trials in 1682 middle-aged and older adults found aerobic training improved VO2max, six-minute walk distance and body mass more than resistance training, while resistance training was better for preserving lean body mass. The authors conclude a combination of both is likely optimal for ageing bodies.

    What it shows: A clear split from good evidence: results pooled from 38 trials with 1682 mostly middle-aged and older adults, and the aerobic advantage for fitness held across sexes, ages and trial lengths. It compares group averages, so it cannot say how to divide training time for any one person.Meta-analysis · Arch Gerontol Geriatr

  18. Nutritionwell supported · human dataAdded 15 August 2026
    Plant protein matches animal protein for strength gains

    A meta-analysis of 16 randomised trials found protein source, animal or plant, made no difference to gains in absolute lean mass or muscle strength. Animal protein showed a small edge on percent lean mass, and adults under 50 gained 0.41 kg more absolute lean mass with it.

    What it shows: Reassuring for plant eaters: results pooled from 16 trials where protein intakes were already above recommended levels, so any advantage of source had room to show and mostly did not. The small animal protein edge appeared mainly in adults under 50, and doing resistance training alongside made no difference to the outcome.Meta-analysis · Nutrients

  19. Recoverywell supported · human dataAdded 15 August 2026
    Heat eases sore muscles as well as ice does

    Across 32 randomised trials in 1098 people, both cold and heat applied within an hour of exercise reduced the pain of delayed onset muscle soreness; cold helped mainly within 24 hours, heat helped both within and beyond 24 hours, hot packs showed the largest effects, and there was no significant difference between cold and heat overall.

    What it shows: Trustworthy on direction, fuzzy on size: results pooled from 32 trials with 1098 people, but the trials varied widely in how heat and cold were applied and the authors themselves call for better studies. Head to head, neither therapy clearly beat the other.Meta-analysis · Phys Ther Sport

  20. Sleepwell supported · human dataAdded 15 August 2026
    Melatonin improves sleep quality, but not for everyone

    A meta-analysis of 23 randomised trials found melatonin supplementation improved sleep quality scores in adults, lowering the Pittsburgh Sleep Quality Index by 1.24 points on average. Benefits were clearest in people with respiratory diseases, metabolic disorders and primary sleep disorders, but absent in those with mental health or neurodegenerative conditions.

    What it shows: Solid but with a catch: results pooled from 23 trials, yet the studies disagreed with each other substantially and nearly all participants had an existing illness, so the benefit may not transfer to a healthy person with occasional bad nights. The average improvement on the sleep questionnaire was modest.Meta-analysis · J Neurol

  21. Tech & Wearableswell supported · human dataAdded 15 August 2026
    Your tracker's calorie burn figure is off by more than 30%

    Across 65 studies of wrist-wearable activity trackers, the Fitbit Charge measured steps with under 25% error and the Apple Watch measured heart rate with under 10% error, but energy expenditure was off by more than 30% for every brand tested.

    What it shows: A trustworthy overview: a sweep of all 65 studies on wrist trackers in the general population. The studies measured accuracy so differently that results could not be combined into one number, so device comparisons are informal rather than head to head.Systematic review · J Med Internet Res

  22. Metabolic & GLP-1preliminary · human dataAdded 15 August 2026
    Cardio moved every marker of metabolic syndrome in older adults with diabetes

    Pooled results from 7 randomised trials found aerobic exercise improved fasting glucose, systolic and diastolic blood pressure, HbA1c, HDL cholesterol and triglycerides in older adults with type 2 diabetes, with no significant adverse effects reported.

    What it shows: Encouraging but thin: results pooled from just 7 trials, and the certainty was rated moderate for blood pressure, low for glucose and very low for everything else. The trials tracked lab markers rather than symptoms or complications, so the real-world payoff is not yet proven.Meta-analysis · Rev Peru Med Exp Salud Publica

  23. Trainingpreliminary · human dataAdded 15 August 2026
    Cardio plus weights calmed inflammation in type 2 diabetes

    Pooled results from 20 trials covering 1,192 adults with type 2 diabetes and overweight or obesity found that combining aerobic and resistance training improved body mass index, blood sugar control, blood pressure, inflammatory markers, cardiorespiratory fitness and quality of life.

    What it shows: Promising but on shaky ground: results pooled from 20 trials in 1,192 people with type 2 diabetes and excess weight, yet the authors themselves rate the underlying evidence as poor quality with uncertain risk of bias. Treat the direction as credible and the sizes as unsettled.Meta-analysis · PeerJ

  24. Supplementswell supported · human dataAdded 15 August 2026
    Creatine plus lifting adds 11.35 kg to lower-body strength, in men at least

    In a meta-analysis of 23 trials in adults under 50, creatine combined with resistance training increased upper-body strength by 4.43 kg and lower-body strength by 11.35 kg on average compared with placebo. Men gained significantly in both, while women, who appeared in only a handful of the trials, showed no significant strength gains.

    What it shows: Strong evidence for men: results pooled from 23 trials consistently showed bigger strength gains when creatine was added to lifting. Women were nearly absent from those trials, so the lack of a clear effect in women may simply reflect too little data rather than a true sex difference.Meta-analysis · Nutrients

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